Nanoemulsion: An Emerging Novel Technology for Improving the Bioavailability of Drugs

Author:

Preeti 12ORCID,Sambhakar Sharda1,Malik Rohit2ORCID,Bhatia Saurabh34ORCID,Al Harrasi Ahmed4ORCID,Rani Chanchal2,Saharan Renu15,Kumar Suresh6,Geeta 1,Sehrawat Renu7

Affiliation:

1. Banasthali Vidyapith, Vanasthali Road, Aliyabad, Rajasthan 304022, India

2. Gurugram Global College of Pharmacy, Haily Mandi Rd, Farukh Nagar, Haryana 122506, India

3. School of Health Sciences, University of Petroleum and Energy Studies, Dehradun, Uttarakhand, India

4. Natural & Medical Sciences Research Centre, University of Nizwa, Birkat Al Mauz, Oman

5. Maharishi Markandeswar Deemed to be University, Mullana, Ambala, Haryana 133203, India

6. Ganpati Institute of Pharmacy, Yamunanagar, Haryana 135102, India

7. School of Medical & Allied Sciences, K R Mangalam University, Gurugram, Haryana 122103, India

Abstract

The pharmaceutical sector has made considerable strides recently, emphasizing improving drug delivery methods to increase the bioavailability of various drugs. When used as a medication delivery method, nanoemulsions have multiple benefits. Their small droplet size, which is generally between 20 and 200 nanometers, creates a significant interfacial area for drug dissolution, improving the solubility and bioavailability of drugs that are weakly water-soluble. Additionally, nanoemulsions are a flexible platform for drug administration across various therapeutic areas since they can encapsulate hydrophilic and hydrophobic medicines. Nanoemulsion can be formulated in multiple dosage forms, for example, gels, creams, foams, aerosols, and sprays by using low-cost standard operative processes and also be taken orally, topically, topically, intravenously, intrapulmonary, intranasally, and intraocularly. The article explores nanoemulsion formulation and production methods, emphasizing the role of surfactants and cosurfactants in creating stable formulations. In order to customize nanoemulsions to particular medication delivery requirements, the choice of components and production techniques is crucial in assuring the stability and efficacy of the finished product. Nanoemulsions are a cutting-edge technology with a lot of potential for improving medication bioavailability in a variety of therapeutic contexts. They are a useful tool in the creation of innovative pharmaceutical formulations due to their capacity to enhance drug solubility, stability, and delivery. Nanoemulsions are positioned to play a crucial role in boosting medication delivery and enhancing patient outcomes as this field of study continues to advance.

Publisher

Hindawi Limited

Subject

General Agricultural and Biological Sciences,General Environmental Science

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