Tissue Engineering Approaches for Enamel, Dentin, and Pulp Regeneration: An Update

Author:

Ahmed Geraldine M.12ORCID,Abouauf Eman A.13,AbuBakr Nermeen14ORCID,Dörfer Christof E.5,El-Sayed Karim Fawzy156

Affiliation:

1. Stem Cell and Tissue Engineering Research Group, Faculty of Dentistry, Cairo University, Cairo, Egypt

2. Department of Endodontics, Faculty of Dentistry, Cairo University, Cairo, Egypt

3. Department of Conservative Dentistry, Faculty of Dentistry, Cairo University, Cairo, Egypt

4. Oral Biology Department, Faculty of Dentistry, Cairo University, Cairo, Egypt

5. Clinic for Conservative Dentistry and Periodontology, School of Dental Medicine, Christian Albrechts University, Kiel, Germany

6. Oral Medicine and Periodontology Department, Faculty of Dentistry, Cairo University, Cairo, Egypt

Abstract

Stem/progenitor cells are undifferentiated cells characterized by their exclusive ability for self-renewal and multilineage differentiation potential. In recent years, researchers and investigations explored the prospect of employing stem/progenitor cell therapy in regenerative medicine, especially stem/progenitor cells originating from the oral tissues. In this context, the regeneration of the lost dental tissues including enamel, dentin, and the dental pulp are pivotal targets for stem/progenitor cell therapy. The present review elaborates on the different sources of stem/progenitor cells and their potential clinical applications to regenerate enamel, dentin, and the dental pulpal tissues.

Publisher

Hindawi Limited

Subject

Cell Biology,Molecular Biology

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