Stereotactic Aspiration Acts as an Effective Treatment for Malignant Middle Cerebral Artery Infarction

Author:

Wang Zhiyu1,Chen Maogang23,Wang Chong1ORCID,Luo Jinbiao4,Sun Shujie1ORCID,Lu Xiangui1ORCID

Affiliation:

1. Department of Neurosurgery, Xuhui Central Hospital, Zhongshan-Xuhui Hospital, Affiliated to Fudan University, Shanghai Clinical Center CAS, Shanghai 200031, China

2. Department of Neurosurgery, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, Jiangsu 211299, China

3. Department of Emergency, The People’s Hospital of Suzhou New District, Suzhou, Jiangsu 215129, China

4. Department of Neurosurgery, Guangzhou First People’s Hospital, Guangzhou, Guangdong 510180, China

Abstract

Objective. This study seeks to explore the efficacy and prognosis of stereotactic aspiration for malignant middle cerebral artery infarction (mMCAI). Methods. A total of 50 mMCAI patients who were diagnosed and treated in our hospital from January 2018 to June 2020 were collected and then randomly divided into control group (decompressive craniectomy, n = 24) and study group (stereotactic aspiration, n = 26). After 1 and 6 months of treatment, the scores of the National Institutes of Health Stroke Scale (NIHSS), Glasgow Coma Scale (GCS), Barthel Index, and modified Rankin Scale (mRS) were used to evaluate the therapeutic effect. Additionally, the mortality and survival rates after treatment were recorded to compare the prognostic effect between the two groups. Results. One month after treatment, the GCS scores and Barthel Index score increased in both the control and study groups and were significantly higher in the study group. The follow-up results at 1 and 6 months after treatment showed that in comparison with the control group, stereotactic aspiration led to a higher survival rate and lower mortality rate; the latter had superior NIHSS score and mRS score and better prognosis. Conclusion. In comparison with decompressive craniectomy, stereotactic aspiration shows outstanding clinical efficacy and more advantages in the treatment of mMCAI. Therefore, stereotactic aspiration is more worthy of clinical application.

Funder

Jiangsu Commission of Health

Publisher

Hindawi Limited

Subject

Health Informatics,Biomedical Engineering,Surgery,Biotechnology

Reference32 articles.

1. Malignant middle cerebral artery infarction treated by catheter aspiration of necrotic brain tissue and lateral ventricular catheter drainage;W. S. Yu;The Journal of Practical Medicine,2019

2. Malignant MCA Infarction: Pathophysiology and Imaging for Early Diagnosis and Management Decisions

3. Hemicraniectomy versus medical treatment with large MCA infarct: a review and meta-analysis

4. Application of improved decompressive craniectomy in treating severe traumatic craniocerebral injury;W. H. Cai;Journal of Traumatic Surgery,2011

5. Sequential-Design, Multicenter, Randomized, Controlled Trial of Early Decompressive Craniectomy in Malignant Middle Cerebral Artery Infarction (DECIMAL Trial)

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