Solitary Fibrous Tumor of the Central Nervous System: A Report of Two Cases with Emphasis on Diagnostic Pitfalls

Author:

Mwazha Absalom12ORCID,Moyeni Nondabula34,Zikalala Zuzile56,Nhlonzi Gamalenkosi Bonginkosi27ORCID

Affiliation:

1. Department of Anatomical Pathology, National Health Laboratory Service, Durban, South Africa

2. Discipline of Anatomical Pathology, University of KwaZulu-Natal, Durban, South Africa

3. Department of Neurosurgery, Inkosi Albert Luthuli Central Hospital, Durban, South Africa

4. Discipline of Neurosurgery, University of KwaZulu-Natal, Durban, South Africa

5. Department of Radiology, Dr. Pixley Ka Isaka Seme Memorial Hospital, Durban, South Africa

6. Discipline of Radiology, University of KwaZulu-Natal, Durban, South Africa

7. Department of Histopathology, Ampath Pathology Laboratories, Pietermaritzburg, South Africa

Abstract

Solitary fibrous tumor (SFT) is a rare primary central nervous system neoplasm that usually presents as a dural-based mass. Awareness of the entity is limited by the rarity of the tumor which renders it prone to misdiagnosis. We present two cases of SFT located in the right parafalx and intraventricular region. The cases were classified as WHO grade 1 and grade 2, respectively. The present study discusses the radiological, histomorphological, and immunohistochemical features of SFT, with emphasis on potential diagnostic pitfalls that may lead to erroneous diagnosis.

Funder

SANLiC Gold

Publisher

Hindawi Limited

Subject

General Medicine

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