Application of Nanomaterials in Stem Cell Regenerative Medicine of Orthopedic Surgery

Author:

Pan Su12,Yu Hongmei3,Yang Xiaoyu1,Yang Xiaohong2,Wang Yan3,Liu Qinyi1,Jin Liliang4,Yang Yudan35ORCID

Affiliation:

1. Department of Orthopedics, The Second Hospital of Jilin University, Changchun, Jilin, China

2. Jilin University School of Pharmaceutical Sciences, Changchun, Jilin, China

3. China-Japan Union Hospital of Jilin University, Changchun, Jilin, China

4. Department of Pathobiological Sciences, Louisiana State University, Baton Rouge, LA, USA

5. State Key Laboratory on Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, Changchun, Jilin, China

Abstract

Regenerative medicine aims to achieve functional rehabilitation of tissue or cells injured through wound, disease, or aging. Recent findings suggest that nanotechnology provides advanced biomaterials with specified morphologies which can create a nanoscale extracellular environment capable of promoting the adhesion and proliferation of stem cells and accelerating stem cell differentiation in a controlled manner in tissue engineering. This review summarizes the biological effects of nanomaterials and their regenerative medicine applications in orthopedic surgery research, including bone, cartilage, tendons, and nerve tissue engineering.

Funder

National Natural Science Foundation of China

Publisher

Hindawi Limited

Subject

General Materials Science

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