Affiliation:
1. Department of Gastrointestinal Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China
2. Department of Clinical Nutrition, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China
Abstract
Purpose. The purpose of this study is to analyze the effect of preoperative waiting time on the short-term outcomes and prognosis in colorectal cancer (CRC) patients. Methods. We retrospectively analyzed 3744 CRC patients who underwent primary CRC surgery at a single clinical medical center from Jan 2011 to Jan 2020. The baseline information, short-term outcomes, overall survival (OS), and disease-free survival (DFS) were compared among the short-waiting group, the intermediate-waiting group, and the long-waiting group. Results. A total of 3744 eligible CRC patients were enrolled for analysis. There were no significant differences in all of the baseline information and short-term outcomes among the three groups. In multivariate analysis, older age (OS:
, HR = 1.947, 95% CI = 1.631–2.324; DFS:
, HR = 1.693, 95% CI = 1.445–1.983), advanced clinical stage (OS:
, HR = 1.301, 95% CI = 1.161–1.457; DFS:
, HR = 1.262, 95% CI = 1.139–1.400), overall complications (OS:
, HR = 1.613, 95% CI = 1.303–1.895; DFS:
, HR = 1.560, 95% CI = 1.312–1.855), and major complications (OS:
, HR = 1.812, 95% CI = 1.338–2.945; DFS:
, HR = 1.647, 95% CI = 1.153–2.352) were independent factors of OS and DFS. In addition, no significant difference was found in all stages (OS,
; DFS,
), stage I (OS,
; DFS,
), stage II (OS,
; DFS,
), or stage III (OS,
; DFS,
) in terms of OS and DFS among the three groups. Conclusion. Preoperative waiting time did not affect the short-term outcomes or prognosis in CRC patients.
Funder
Chongqing Key Diseases Research and Application Demonstration Program
Subject
Gastroenterology,Hepatology,General Medicine