The Influence of Different Types of Diabetes on Vascular Complications

Author:

Wei Jiahua1ORCID,Tian Jiaxing2ORCID,Tang Cheng1ORCID,Fang Xinyi23ORCID,Miao Runyu23,Wu Haoran3ORCID,Wang Xiuge4ORCID,Tong Xiaolin12ORCID

Affiliation:

1. Changchun University of Chinese Medicine, Changchun 130117, China

2. Department of Endocrinology, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China

3. Beijing University of Traditional Chinese Medicine, Beijing 100029, China

4. Affiliated Hospital of Changchun University of Traditional Chinese Medicine, Changchun 130021, China

Abstract

The final outcome of diabetes is chronic complications, of which vascular complications are the most serious, which is the main cause of death for diabetic patients and the direct cause of the increase in the cost of diabetes. Type 1 and type 2 diabetes are the main types of diabetes, and their pathogenesis is completely different. Type 1 diabetes is caused by genetics and immunity to destroy a large number of β cells, and insulin secretion is absolutely insufficient, which is more prone to microvascular complications. Type 2 diabetes is dominated by insulin resistance, leading to atherosclerosis, which is more likely to progress to macrovascular complications. This article explores the pathogenesis of two types of diabetes, analyzes the pathogenesis of different vascular complications, and tries to explain the different trends in the progression of different types of diabetes to vascular complications, in order to better prevent diabetes and its vascular complications.

Funder

National Administration of Traditional Chinese Medicine

Publisher

Hindawi Limited

Subject

Endocrinology,Endocrinology, Diabetes and Metabolism

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