Local and Remote Postconditioning Decrease Intestinal Injury in a Rabbit Ischemia/Reperfusion Model-Reference-Cited by-全球学者库

Local and Remote Postconditioning Decrease Intestinal Injury in a Rabbit Ischemia/Reperfusion Model

Published:2016 Issue: Volume:2016 Page:1-7
ISSN:1687-6121
Container-title:Gastroenterology Research and Practice
language:en
Short-container-title:Gastroenterology Research and Practice

Author:

Yang Mu¹,Dong Jian-Xin¹,Li Lu-Bin¹,Che Hai-Jie¹,Yong Jun¹,Song Fu-Bo¹,Wang Tao¹,Zhang Jv-Wen¹

Affiliation:

1. Department of Vascular Surgery, Yantai Yuhuangding Hospital, The Affiliated Hospital of Medical College, Qingdao University, Yantai 264000, China

Abstract

Intestinal ischemia/reperfusion (I/R) injury is a significant problem that is associated with high morbidity and mortality in critical settings. This injury may be ameliorated using postconditioning protocol. In our study, we created a rabbit intestinal I/R injury model to analyze the effects of local ischemia postconditioning (LIPo) and remote ischemia postconditioning (RIPo) on intestinal I/R injury. We concluded that LIPo affords protection in intestinal I/R injury in a comparable fashion with RIPo by decreasing oxidative stress, neutrophil activation, and apoptosis.

Publisher

Hindawi Limited

Subject

Gastroenterology,Hepatology

Link

http://downloads.hindawi.com/journals/grp/2016/2604032.pdf

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