Importanţa microbiomului în obezitatea pediatrică

Abstract

Childhood involves aspects for interventions that con­fi­gure the microbiome to alleviate obesity-related dis­tur­bances. Children with obesity have gut microbiota com­po­si­tio­nal and functional differences, including in­creased pro­in­flam­matory bacterial characteristics. Re­sto­ra­tion of the gut microbiota to a healthy state may ame­lio­rate conditions associated with obesity and help main­tain a healthy weight. This review brings to the fore the consequences and aspects of childhood obesity, the im­por­tance of the developing microbiome in establishing meta­bolic path­ways, and the therapeutic attitude. It contributes basically to denote future research directions for the potential develop­ment of microbiome-based therapeutics to treat obesity.