Author:
Luks Andrew M.,Swenson Erik R.,Bärtsch Peter
Abstract
At any point 1–5 days following ascent to altitudes ≥2500 m, individuals are at risk of developing one of three forms of acute altitude illness: acute mountain sickness, a syndrome of nonspecific symptoms including headache, lassitude, dizziness and nausea; high-altitude cerebral oedema, a potentially fatal illness characterised by ataxia, decreased consciousness and characteristic changes on magnetic resonance imaging; and high-altitude pulmonary oedema, a noncardiogenic form of pulmonary oedema resulting from excessive hypoxic pulmonary vasoconstriction which can be fatal if not recognised and treated promptly. This review provides detailed information about each of these important clinical entities. After reviewing the clinical features, epidemiology and current understanding of the pathophysiology of each disorder, we describe the current pharmacological and nonpharmacological approaches to the prevention and treatment of these diseases.
Publisher
European Respiratory Society (ERS)
Subject
Pulmonary and Respiratory Medicine
Reference139 articles.
1. Bartsch P , Bailey DM . Acute mountain sickness and high altitude cerebral oedema. In: Swenson ER , Bartsch P , eds. High Altitude Human Adaptation to Hypoxia. New York, Springer, 2014; pp. 379–404.
2. Roach RC , Bartsch P , Hackett PH , et al. The Lake Louise acute mountain sickness scoring system. In: Sutton JR , Coates G , Houston CS , eds. Hypoxia and Molecular Medicine: Proceedings of the 8th International Hypoxia Symposium, Lake Louise, Alberta, Canada. Burlington, Vt, Queen City Printers, 1993; pp. 272–274.
3. Procedures for the measurement of acute mountain sickness;Sampson;Aviat Space Environ Med,1983
4. Con: Headache Should not Be a Required Symptom for the Diagnosis of Acute Mountain Sickness
5. The cerebral effects of ascent to high altitudes
Cited by
266 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献