Affiliation:
1. Faculty of Exact Sciences and Technology, Organic Catalysis and Biocatalysis Laboratory – (LACOB), Federal University of Grande Dourados – UFGD, Dourados/MS, Brazil
Abstract
Background:
Sulfur-containing compounds represent an important class of chemical compounds due
to their wide range of biological and pharmaceutical properties. Moreover, sulfur-containing compounds may be
applied in other fields, such as biological, organic, and materials chemistry. Several studies on the activities of
sulfur compounds have already proven their anti-inflammatory properties and use to treat diseases, such as
Alzheimer’s, Parkinson’s, and HIV. Moreover, examples of sulfur-containing compounds include dapsone,
quetiapine, penicillin, probucol, and nelfinavir, which are important drugs with known activities.
Objective:
This review will focus on the synthesis and application of some sulfur-containing compounds used to
treat several diseases, as well as promising new drug candidates.
Results:
Due to the variety of compounds containing C-S bonds, we have reviewed the different synthetic
routes used toward the synthesis of sulfur-containing drugs and other compounds.
Funder
Fundação de Apoio ao Desenvolvimento do Ensino, Ciência e Tecnologia do Estado de Mato Grosso do Sul
Conselho Nacional de Desenvolvimento Científico e Tecnológico
Publisher
Bentham Science Publishers Ltd.
Subject
Organic Chemistry,Biochemistry
Cited by
35 articles.
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