Affiliation:
1. Institute of Biotechnology, Amity University, Rajasthan, 303007, India
2. Department of Microbiology,
ICMR-Regional Medical Research Centre, Bhubaneswar, 751023, India
Abstract
Abstract:
It is becoming increasingly difficult to treat bacterial infections with conventional
antibiotics as resistance increases with time. Common antibiotics have been irrationally used
in the general community, which has resulted in the selection of antibiotic-resistant genes.
Despite various modifications that have been done to restore the antimicrobial activities of
conventional antibiotics against an array of multi-drug resistant (MDR) strains, it has been
unattainable to overcome this hurdle for a long time. Parallelly, the search for a new and alternative
drug has become a high priority in every part of the world.
:
In the last two decades, immense interest has grown in natural products as alternative therapeutics
due to their lower toxicity, chemical group diversity and biochemical specificity,
which are the upper hand compared to antibiotics. Essential oils are naturally found phytochemicals
obtained from approximately 60 families of plants. These are composed of 20 to 60
different bioactive components at different concentrations and have already been reported for
their antibacterial, antifungal, antiviral, anti-parasitic, insecticidal activities, antioxidant and
antiseptic properties. This review focuses on antimicrobial activities, detailed mode of action
and the latest progress in the research on the essential oil.
Publisher
Bentham Science Publishers Ltd.
Subject
Pharmacology (medical),Infectious Diseases,Drug Discovery