Affiliation:
1. Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University, Greater Noida, Uttar Pradesh,
India
Abstract
Abstract:
When compared to chemical medicines, herbal medicines have the greatest therapeutic
benefit while having fewer harmful side effects. Many different components in herbs have an anticancer
impact, but the exact mechanism of how they work is unknown. Some herbal medicines
have even been shown to trigger autophagy, a process that has shown promise as a potential cancer
treatment. In the past ten years, autophagy has come to be recognised as a crucial mechanism in
the maintenance of cellular homeostasis, which has led to the discovery of its implications in the
pathology of the majority of cellular environments as well as human disorders. Autophagy is a
catabolic process that is used by cells to maintain their homeostasis. This process involves the
degradation of misfolded, damaged, and excessive proteins, as well as nonfunctional organelles,
foreign pathogens, and other cellular components. Autophagy is a highly conserved process. In
this review article, several naturally occurring chemicals are discussed. These compounds offer
excellent prospects for autophagy inducers, which are substances that can hasten the death of cells
when used as a complementary or alternative treatment for cancer. It requires additional exploration
in preclinical and clinical investigations, notwithstanding recent advances in therapeutic medications
or agents of natural products in numerous cancers. These advancements have been made
despite the need for further investigation.
Publisher
Bentham Science Publishers Ltd.
Subject
Pharmaceutical Science,Biotechnology