Therapeutic Implications of Curcumin in the Treatment of Inflammatory Eye Diseases: A Review-Reference-Cited by-同舟云学术

Therapeutic Implications of Curcumin in the Treatment of Inflammatory Eye Diseases: A Review

Published:2023-03 Issue:4 Volume:24 Page:553-561
ISSN:1389-2010
Container-title:Current Pharmaceutical Biotechnology
language:en
Short-container-title:CPB

Author:

Thiruvengadam Muthu¹²,Heydari Mojtaba³,Khalili Mohammad Reza³,Nowroozzadeh Mohammad Hossein³,Bamdad Shahram³,Sahebkar Amirhossein⁴⁵,Shariati Mohammad Ali⁶

Affiliation:

1. Department of Applied Bioscience, College of Life and Environmental Sciences, Konkuk University, Seoul, 05029, Korea

2. Department of Microbiology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai 600077, India

3. Poostchi Ophthalmology Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

4. Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran

5. Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

6. K.G. Razumovsky Moscow State University of Technologies and Management (the First Cossack University), Moscow 109004, Russian Federation

Abstract

Abstract: Curcumin is the main active constituent of the medicinal plant Curcuma longa L., used traditionally as a medicinal spice in several ancient civilizations. Different preclinical and clinical studies support the anti-inflammatory properties of curcumin in various inflammatory diseases. As inflammation has an essential role in the pathophysiology of many ocular diseases, curcumin has been suggested as a promising therapeutic agent with anti-inflammatory properties. Based on the extent of experimental and clinical evidence, curcumin can exert protective effects against the corneal, uveal, retinal, optic nerve, orbital, and lacrimal gland inflammatory disorders. Herein, the available literature on the beneficial effects of curcumin in inflammatory eye diseases is reviewed. The limitations and future directions of these investigations are also discussed.

Publisher

Bentham Science Publishers Ltd.

Subject

Pharmaceutical Science,Biotechnology

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