Affiliation:
1. Faculty of Bioengineering, Zhuhai Campus of Zunyi Medical University, Zhuhai, 519041, China
Abstract
Abstract:
Tribe Delphineae in the family Ranunculaceae is composed of the genera Aconitum
and Delphinium and is a resource plant group with important medicinal value. Alkaloids
are the main active ingredients in these two genera, with previous studies primarily focusing
on diterpenoid alkaloids. Recent comprehensive studies of the chemical components have
uncovered numerous non-diterpenoid alkaloids of diverse structural types, such as amides,
isoquinolines, pyridines, phenethylamines, and diazines. These compounds exhibit various
biological activities, including cardiotonic, antitumor, and antibacterial effects. In this paper,
the structural characteristics and biological activities of 156 non-diterpenoid alkaloids reported
in Aconitum and Delphinium are reviewed for the first time to provide references for
the efficient utilization of plant resources of these two genera.
Funder
National Natural Science Foundation of China
Applied Basic Research Project of Zhuhai City
University Characteristic Innovation Project of Guangdong Province
Publisher
Bentham Science Publishers Ltd.