Nano Drug Delivery Systems: A Mini-review

Author:

Syam Kumar Valli Nachiyar1ORCID,Sunkar Swetha1ORCID,Selvaraj Karthick Raja Namasivayam2,Nellore Jayshree1ORCID

Affiliation:

1. Department of Biotechnology, Sathayabama Institute of Science and Technology, Jeppiaar Nagar, OMR, Sholinganallur, Chennai, 600 119, India

2. Department of Research and Innovation, Saveetha School of Engineering, SIMATS Deemed University, Chennai 602 105, India

Abstract

Abstract: Medical nanotechnology is surfacing as a challenging arena covering new biomedical applications, such as drug delivery, treatment, nano diagnosis, controlled drug release, regenerative medicine, and disease prevention. The recent developments in the field of Nanotechnology have enabled the nanostructures to overcome the problems associated with drug delivery making them the promising agents for site-specific drug delivery with reduced side effects and the best treatment outcome. These nanodrug delivery systems are designed in such a way that they can breach the biological barrier and deliver the drug in a site-specific manner. They enhance the effectiveness of drugs by increasing the stability and water solubility of drugs and by increasing the rate at which these nano drug complexes are taken up by the cells and tissues. Dendrimers, nanocrystals, nano-polymer NPs, and liposomes are futuristic nano-based drug delivery systems. Smart polymers are future drug-delivery systems with cutting-edge precise technology that are employed in effective cellular targeting based on temperature, pH, photoresponsive, conductive and magnetic responsive smart polymers. This review provides a comprehensive view of various nanostructures and their application in drug delivery.

Publisher

Bentham Science Publishers Ltd.

Subject

General Engineering,General Materials Science

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