Chrysin Effect Against Gastric Cancer: Focus on its Molecular Mechanisms-Reference-Cited by-同舟云学术

Chrysin Effect Against Gastric Cancer: Focus on its Molecular Mechanisms

Published:2023-11 Issue:7 Volume:16 Page:
ISSN:1874-4672
Container-title:Current Molecular Pharmacology
language:en
Short-container-title:CMP

Author:

Samarghandian Saeed¹,Alavi Dana Seyyed Mohammad Matin²,Farkhondeh Tahereh³,Aschner Michael⁴,Darroudi Majid⁵,Samini Helia⁶

Affiliation:

1. Healthy Ageing Research Centre, Neyshabur University of Medical Sciences, Neyshabur, Iran

2. Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

3. Department of Toxicology and Pharmacology, School of Pharmacy, Birjand University of Medical Sciences, Birjand, Iran

4. Department of Molecular Pharmacology, Albert Einstein College of Medicine, Forchheimer 2091300 Morris Park Avenue, Bronx, New York, USA

5. Department of Basic Sciences, Neyshabur University of Medical Sciences, Neyshabur, Iran

6. Dentistry Student of Mashhad Medical University, Mashhad, Iran

Abstract

Abstract: Gastric cancer is one of the most prevalent cancers in the world. Various therapeutic modalities have been used for its treatment, but all exhibit severe side effects, establishing the need for novel approaches. Chrysin is a phytomedicine compound belonging to the flavonoid group. It is found in honey and many plants. Its antitumor effects have been documented against gastric cancer cell lines in vitro, establishing its effects are mediated via different pathways and the expression of miRNA. In this review, we summarize the available literature on chrysin and its effects on gastric cancer, focusing on the cellular mechanisms it targets.

Publisher

Bentham Science Publishers Ltd.

Subject

General Health Professions

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