Vaccines for COVID-19: A Review of Feasibility and Effectiveness-Reference-Cited by-同舟云学术

Vaccines for COVID-19: A Review of Feasibility and Effectiveness

Published:2021-09-23 Issue: Volume:21 Page:
ISSN:1871-5265
Container-title:Infectious Disorders - Drug Targets
language:en
Short-container-title:IDDT

Author:

Mehraeen Esmaeil¹,Dadras Omid²,Afsahi Amir Masoud³,Karimi Amirali⁴,MohsseniPour Mehrzad⁵,Mirzapour Pegah⁵,Barzegary Alireza⁶,Behnezhad Farzane⁷,Habibi Pedram⁵,Salehi Mohammad Amin⁵,Vahedi Farzin⁴,Heydari Mohammad¹,Kianzad Shaghayegh⁸,Moradmand-Badie Banafsheh⁹,Javaherian Mohammad¹⁰,SeyedAlinaghi SeyedAhmad⁵,Sabatier Jean-Marc¹¹

Affiliation:

1. Department of Health Information Technology, Khalkhal University of Medical Sciences, Khalkhal, Iran

2. Department of Global Health and Socioepidemiology, Graduate School of Medicine, Kyoto University, Kyoto, Japan

3. Department of Radiology, School of Medicine, University of California, San Diego [UCSD], California, United States

4. School of medicine, Tehran University of Medical Sciences, Tehran, Iran

5. Iranian Research Center for HIV/AIDS, Iranian Institute for Reduction of High Risk Behaviors, Tehran University of Medical Sciences, Tehran, Iran

6. School of medicine, Islamic Azad University, Tehran, Iran

7. Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran

8. School of Medicine, Iran University of Medical Sciences, Tehran ‎7134845794, Iran

9. Black Dog Institute, University of New South Wales, Sydney, Australia

10. Department of Physiotherapy, Tehran University of Medical Sciences, Tehran, Iran

11. Université Aix-Marseille, Institut deNeuro-physiopathologie [INP],UMR 7051, Faculté de Pharmacie,27 Bd Jean Moulin, 13385Marseille Cedex, France

Abstract

Introduction: Many potential vaccines for COVID-19 are being studied, and several studies have reported the results of these vaccines. We aimed to review the current evidence of the feasibility and effectiveness of Vaccines for COVID-19. Methods: A search was carried out utilizing the keywords in the online databases, including Scopus,Web of Science, PubMed, Embase, and Cochrane. We included both human and non-human studies because of the vaccine novelty, which could limit our ability to include sufficient human studies. Results: The review of studies showed that several SARS-CoV-2 vaccines are under development; different platforms are being used, including eight vaccines are adenovirus-based vectors, six vaccines are RNA-based formulations, one vaccine is DNA-based formulations, and other vaccines are using other platforms, including lipid nano particles. Conclusion: It is crucial to gather as much clinically relevant evidence as possible regarding the immunogenicity, efficacy, and safety profiles of these vaccines and adhere wisely to CDC protocols and guidelines of vaccine production.

Publisher

Bentham Science Publishers Ltd.

Subject

Microbiology (medical),Pharmacology,Molecular Medicine,General Medicine

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