Synthesis and Biological Activity Study of Tanshinone Derivatives: A Literature and Patent Review-Reference-Cited by-同舟云学术

Synthesis and Biological Activity Study of Tanshinone Derivatives: A Literature and Patent Review

Published:2020-11-20 Issue:28 Volume:20 Page:2520-2534
ISSN:1568-0266
Container-title:Current Topics in Medicinal Chemistry
language:en
Short-container-title:CTMC

Author:

Huang He¹,Song Chuanjun¹,Chang Junbiao¹

Affiliation:

1. College of Chemistry, Zhengzhou University, Zhengzhou 450001, China

Abstract

Tanshinones are a class of bioactive compounds present in the Chinese herbal medicine Danshen (Salvia miltiorrhiza Bunge), containing among others, abietane diterpene quinone scaffolds. Chemical synthesis and biological activity studies of natural and unnatural tanshinone derivatives have been reviewed in this article.

Funder

NSFC-Henan

Publisher

Bentham Science Publishers Ltd.

Subject

Drug Discovery,General Medicine

Reference83 articles.

1. Zhou L.; Zuo Z.; Chow M.S.S.; Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use. J Clin Pharmacol 2005,45(12),1345-1359

2. Wang B.; Salvia miltiorrhiza: Chemical and pharmacological review of a medicinal plant. J Med Plants Res 2010,4(25),2813-2820

3. Su C-Y.; Ming Q-L.; Rahman K.; Han T.; Qin L-P.; Salvia miltiorrhiza: Traditional medicinal uses, chemistry, and pharmacology. Chin J Nat Med 2015,13(3),163-182

4. Wang X.; Morris-Natschke S.L.; Lee K-H.; New developments in the chemistry and biology of the bioactive constituents of Tanshen. Med Res Rev 2007,27(1),133-148

5. Cai Y.; Zhang W.; Chen Z.; Shi Z.; He C.; Chen M.; Recent insights into the biological activities and drug delivery systems of tanshinones. Int J Nanomedicine 2016,11,121-130

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Tanshinone IIA alleviates cardiac hypertrophy through m6A modification of galectin-3;Bioengineered;2022-02-01

2. Design, synthesis and biological evaluation of tanshinone IIA-based analogues: Potent inhibitors of microtubule formation and angiogenesis;European Journal of Medicinal Chemistry;2021-11

3. Privileged Scaffolds for Drug Design and Activity Improvement-Part I;Current Topics in Medicinal Chemistry;2020-11-20