Challenges and Discoveries in Polypharmacology

Author:

Scotti Marcus T.1,Scotti Luciana1

Affiliation:

1. Federal University of Paraíba, Campus I, 58051-900, João Pessoa-PB, Brazil

Abstract

Publisher

Bentham Science Publishers Ltd.

Subject

Drug Discovery,General Medicine

Reference10 articles.

1. Lorenzo V. P.; Lucio A.; Scotti L.; Tavares J. F.; Barbosa J. M.; Lima T. K. D.; Rocha J. D.; Scotti M. T.; Structure- and Ligand-Based Approaches to Evaluate Aporphynic Alkaloids from Annonaceae as Multi-Target Agent Against Leishmania donovani. Current Pharmaceutical Design 2016,22(34),5196-5203

2. Luis J. A. D.; Costa N. A. D.; Luis C. C. S.; Lira B. F.; Athayde P. F.; Lima T. K. D.; Rocha J. C.; Scotti L.; Scotti M. T.; Synthesis of New Cyclic Imides Derived from Safrole, Structure- and Ligand-based Approaches to Evaluate Potential New Multitarget Agents Against Species of Leishmania. Medicinal Chemistry 2020,16(1),39-51

3. Luis J. A. D.; Souza H. D. D.; Lira B. F.; Alves F. D.; de Athayde P. F.; Lima T. K. D.; Rocha J. C.; Mendonca F. J. B.; Scotti L.; Scotti M. T.; Combined structure- and ligand-based virtual screening aiding discovery of selenoglycolicamides as potential multitarget agents against Leishmania species. Journal of Molecular Structure 2019,1198

4. Maia M. D.; Rodrigues G. C. S.; de Sousa N. F.; Scotti M. T.; Scotti L.; Mendonca F. J. B.; Identification of New Targets and the Virtual Screening of Lignans against Alzheimer's Disease. Oxidative Medicine and Cellular Longevity 2020,2020

5. Maia M. D.; Silva J. P. E.; Nunes T. A. D.; de Sousa J. M. S.; Rodrigues G. C. S.; Monteiro A. F. M.; Tavares J. F.; Rodrigues K. A. D.; Mendonca F. J. B.; Scotti L.;; et al. Virtual Screening and the In Vitro Assessment of the Antileishmanial Activity of Lignans. Molecules 2020,25(10)

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