Affiliation:
1. Department of Pharmaceutical Sciences, M.D.U, Rohtak, Haryana, India
2. Department of Pharmacognosy and Phytochemistry, Hindu College of Pharmacy, Sonepat, Haryana, India
Abstract
Background:
Human’s existence has become more stressful these days, most likely for the
sake of improving one's lifestyle and fulfilling one's aspirations and needs. Depression is the most frequent
neurological disorder, which affects millions of individuals worldwide. In clinical research, depression
is the second most frequent chronic disease. A variety of herbal medications thought to have
antidepressant-like effects have been reported in ancient pharmacopoeias from around the world. These
provide several prospective chemicals that could be developed into modern mental medications
while also causing no noticeable negative effects.
Objective:
The review is written to provide herbal treatment and comprehensive information about depression.
Methods:
Plants and plant formulations that were found effective in the treatment of depression are
thoroughly reviewed. The antidepressant efficacies of medicinal plants, as well as their dosages, are
investigated using experimental models. The review article contains 140 plants possessing antidepressant
properties, 11 commercial formulations, and 25 active/isolated ingredients, as well as their chemical
structure, which have been thoroughly reviewed with antidepressant activity after studying 283
references.
Results:
Literature revealed that a variety of medicinal plants are effective for the treatment of depression
such as Hypericum perforatum, Catha edulis, Tinospora cordifolia, Curcuma longa, Ferula foetida,
Rhodio larosea, Glycyrrhiza glabra, Crocus sativus, Ocimumba silicum and Embelica officinalis.
Conclusion:
Potential compounds isolated from medicinal plants for the treatment of depressive
disorders need to be established and herbal plant research could aid in this endeavour.
Publisher
Bentham Science Publishers Ltd.
Subject
Pharmacology,General Neuroscience
Cited by
3 articles.
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