The Effects of Vitamin Therapy on ASD and ADHD: A Narrative Review

Author:

Olangian-Tehrani Sepehr12ORCID,Poudineh Mohadeseh3ORCID,Parvin Sadaf1ORCID,Omidali Mehrnia1ORCID,Nikzad Farhad42ORCID,Mohammadyari Fatemeh5ORCID,Sadeghi Poor Ranjbar Fatemeh6ORCID,Rasouli Fayaz7ORCID,Nanbakhsh Sepehr12ORCID

Affiliation:

1. School of Medicine, Iran University of Medical Sciences, Tehran, Iran

2. Avicennet, Tehran, Iran

3. School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran

4. Student Research Committee, International Campus, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

5. School of Medicine, Guilan University of Medical Sciences, Rasht, Iran

6. School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

7. Department of Medicine, Mashhad Islamic Azad University, Mashhad, Iran

Abstract

Abstract: The effects of a sufficient amount of vitamins and nutrients on the proper function of the nervous system have always been regarded by scientists. In recent years, many studies have been done on controlling or improving the symptoms of neurological and behavioral disorders created by changes in the level of vitamins and other nutrition, such as omega-3 and iron supplements. Autism spectrum disorder (ASD) is a neurodevelopmental disorder that disrupts individual communication, especially in social interactions. Its symptoms include anxiety, violence, depression, self-injury, trouble with social contact and pervasive, stereotyped, and repetitive behavior. ASD is most noticeable in early childhood. Attention Deficit Hyperactivity Disorder (ADHD) is a lasting pattern of inattention with or without hyperactivity that causes functional disruption in daily life. ADHD symptoms included; impulsivity, hyperactivity, inattention, restlessness, talkativeness, excessive fidgeting in situations such as sitting, meetings, lectures, or at the movies, boredom, inability to make decisions, and procrastination. The exact etiology of ADHD has not yet been found, but several observations have assumed the reduced function of the brain leads to deficits in motor planning and cognitive processing. It has been shown that Pro-inflammatory cytokines and oxidative stress biomarkers could be increased in both ASD and ADHD. Several studies have been done to illustrate if vitamins and other dietary supplements are effective in treating and preventing ASD and ADHD. In this review, we aim to evaluate the effects of vitamins and other dietary supplements (e.g., melatonin, zinc supplements, magnesium supplements) on ASD and ADHD.

Publisher

Bentham Science Publishers Ltd.

Subject

Pharmacology,General Neuroscience

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