P-coumaric Acid: Advances in Pharmacological Research Based on Oxidative Stress

Author:

Chen Feixiang1ORCID,Zhang Xinxin1,Wang Junxiang2,Wang Fukai3,Mao Jinlong1

Affiliation:

1. School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, China

2. Experimental Center of Shandong University of Traditional Chinese Medicine, Jinan, China

3. Breast Cancer Center, Shandong Cancer Hospital and Institute, Jinan, China

Abstract

Abstract: P-coumaric acid is an important phenolic compound that is mainly found in fruits, vegetables, grains, and fungi and is also abundant in Chinese herbal medicines. In this review, the pharmacological research progress of p-coumaric acid in recent years was reviewed, with emphasis on its role and mechanism in oxidative stress-related diseases, such as inflammation, cardiovascular diseases, diabetes, and nervous system diseases. Studies have shown that p-coumaric acid has a positive effect on the prevention and treatment of these diseases by inhibiting oxidative stress. In addition, p-coumaric acid also has anti-tumor, antibacterial, anti-aging skin and other pharmacological effects. This review will provide reference and inspiration for further research on the pharmacological effects of p-coumaric acid.

Funder

Shandong Provincial Natural Science Foundation, China

Publisher

Bentham Science Publishers Ltd.

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