Reperfusion Cardiac Injury: Receptors and the Signaling Mechanisms-Reference-Cited by-同舟云学术

Reperfusion Cardiac Injury: Receptors and the Signaling Mechanisms

Published:2022-09 Issue:5 Volume:18 Page:
ISSN:1573-403X
Container-title:Current Cardiology Reviews
language:en
Short-container-title:CCR

Author:

Maslov Leonid N.¹,Popov Sergey V.¹,Mukhomedzyanov Alexandr V.¹,Naryzhnaya Natalia V.¹,Voronkov Nikita S.¹,Ryabov Vyacheslav V.¹,Boshchenko Alla A.¹,Khaliulin Igor²,Prasad N. Rajendra³,Fu Feng⁴,Pei Jian-Ming⁴,Logvinov Sergey V.⁵,Oeltgen Peter R.⁶

Affiliation:

1. Laboratory of Experimental Cardiology, Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk, Russia

2. School of Clinical Sciences, University of Bristol, Bristol Royal Infirmary, Bristol, UK

3. Department of Biochemistry and Biotechnology, Faculty of Science, Annamalai University, Annamalainagar, Tamilnadu, India

4. Department of Physiology and Pathophysiology, National Key Discipline of Cell Biology, School of Basic Medicine, Fourth Military Medical University, Xi\'an, China

5. Department of Histology, Embryology and Cytology, Siberian State Medical University, 634055 Tomsk, Russia

6. Department of Pathology, University of Kentucky College of Medicine, Lexington, KY, USA

Abstract

Abstract:It has been documented that Ca2+ overload and increased production of reactive oxygen species play a significant role in reperfusion injury (RI) of cardiomyocytes. Ischemia/reperfusion induces cell death as a result of necrosis, necroptosis, apoptosis, and possibly autophagy, pyroptosis and ferroptosis. It has also been demonstrated that the NLRP3 inflammasome is involved in RI of the heart. An increase in adrenergic system activity during the restoration of coronary perfusion negatively affected cardiac resistance to RI. Toll-like receptors are involved in RI of the heart. Angiotensin II and endothelin-1 aggravated ischemic/reperfusion injury of the heart. Activation of neutrophils, monocytes, CD4+ T-cells and platelets contributes to cardiac ischemia/reperfusion injury. Our review outlines the role of these factors in reperfusion cardiac injury.

Funder

Russian Foundation of Basic Research

National Natural Science Foundation of China

Publisher

Bentham Science Publishers Ltd.

Subject

Cardiology and Cardiovascular Medicine,General Medicine

Reference187 articles.

1. Olier I.; Sirker A.; Hildick-Smith D.J.R.; British cardiovascular intervention society and the national institute for cardiovascular out-comes research. Association of different antiplatelet therapies with mortality after primary percutaneous coronary intervention. Heart 2018,104(20),1683-1690

2. Maslov L.N.; Barbarash O.L.; Pharmacological approaches to limiting the infarct zone size in patients with acute myocardial infarction: Anal-ysis of clinical data. Eksp Klin Farmakol 2018,81,34-41

3. Cohen M.V.; Yang X.M.; Downey J.M.; The pH hypothesis of postconditioning: Staccato reperfusion reintroduces oxygen and perpetuates myocardial acidosis. Circulation 2007,115(14),1895-1903

4. Ong S.B.; Samangouei P.; Kalkhoran S.B.; Hausenloy D.J.; The mitochondrial permeability transition pore and its role in myocardial ischemia reperfusion injury. J Mol Cell Cardiol 2015,78,23-34

5. Zhao Z.Q.; Nakamura M.; Wang N.P.; Dynamic progression of contractile and endothelial dysfunction and infarct extension in the late phase of reperfusion. J Surg Res 2000,94(2),133-144

Cited by 12 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Endothelial Cell Apoptosis but Not Necrosis Is Inhibited by Ischemic Preconditioning;International Journal of Molecular Sciences;2024-01-19

2. Ferroptosis, a Regulated Form of Cell Death, as a Target for the Development of Novel Drugs Preventing Ischemia/Reperfusion of Cardiac Injury, Cardiomyopathy and Stress-Induced Cardiac Injury;International Journal of Molecular Sciences;2024-01-11

3. Design of a Zn-based nanozyme injectable multifunctional hydrogel with ROS scavenging activity for myocardial infarction therapy;Acta Biomaterialia;2024-01

4. Alpha-lipoic acid enhances ischemic postconditioning-mediated improvement of myocardial infarction and apoptosis in diabetic rats with ischemia/reperfusion injury;Canadian Journal of Physiology and Pharmacology;2023-12-01

5. δ-Opioid receptor as a target for the creation of peptide drugs that increase cardiac resistance to reperfusion;The Siberian Journal of Clinical and Experimental Medicine;2023-08-14