Affiliation:
1. Department of Structural and Functional Biology, Institute of Biology, University of Campinas, Campinas, Brazil
Abstract
In general, postmenopausal women present higher mortality, and worse prognosis after
myocardial infarction (MI) compared to men, due to estrogen deficiency. After MI, cardiovascular
alterations occur such as the autonomic imbalance and the pro-inflammatory cytokines increase. In
this sense, therapies that aim to minimize deleterious effects caused by myocardial ischemia are
important. Aerobic training has been proposed as a promising intervention in the prevention of cardiovascular
diseases. On the other hand, some studies have attempted to identify potential biomarkers
for cardiovascular diseases or specifically for MI. For this purpose, metabolomics has been used
as a tool in the discovery of cardiovascular biomarkers. Therefore, the objective of this work is to
discuss the changes involved in ovariectomy, myocardial infarction, and aerobic training, with emphasis
on inflammation and metabolism.
Publisher
Bentham Science Publishers Ltd.
Subject
Cardiology and Cardiovascular Medicine,General Medicine
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