Prenatal Learning and Memory: Review on the Impact of Exposure

Author:

Chamallamudi Mallikarjuna Rao1,Kumar Nitesh23,Kamath Sushmitha1,Kumar Gautam1,Vaishali K.4,Sinha Mukesh Kumar4,Amin Revati4

Affiliation:

1. Department of Pharmacology, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, Karnataka- 576104, India

2. Department of Pharmacology, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, Karnataka- 576104, India

3. Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Hajipur-844102, Bihar, India

4. Department of Physiotherapy, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal, Karnataka- 576104, India

Abstract

Background: Prenatal Learning is a topic still debated for its existence, although the concept is well known since ancient times. Objective: The present review highlights the impact of various stimuli on learning and memory in prenatal and postnatal life. Method: For review, various articles from preclinical and clinical studies providing early pieces of evidence of prenatal learning to date were included based on the relevancy of the databases, namely, Scopus, Pubmed, and Google Scholar. Results: Learning is the process of acquiring skills/ preferences/ habits from the experiences of the exposures of the past. These exposures are the stimuli, which help in categorizing learning into as-sociated or nonassociated learning. The stimuli of adults related to auditory, gustatory, olfactory, visual, touch, etc. are also accessible to the prenatal life in utero either directly or indirectly through the mother. The effects of these stimuli are remarkable during prenatal life and can be seen clearly in infants. These stimuli play an important role in prenatal learning and contribute to neuronal de-velopment. The present review summarizes the pieces of evidence for each of these types of learn-ing & their impact on the ex utero life, a futuristic view & the scope of understanding prenatal learning. The review also elucidates the factors affecting prenatal learning. Conclusion: Studies from clinical and preclinical studies reflected the impacts of several aspects of an infant’s life and the memory created during prenatal life was found to be most likely carried on to postnatal life.

Publisher

Bentham Science Publishers Ltd.

Subject

Pediatrics, Perinatology and Child Health

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