A Review of the Diagnosis and Treatment of Necrotizing Enterocolitis-Reference-Cited by-同舟云学术

A Review of the Diagnosis and Treatment of Necrotizing Enterocolitis

Published:2023-08 Issue:3 Volume:19 Page:285-295
ISSN:1573-3963
Container-title:Current Pediatric Reviews
language:en
Short-container-title:CPR

Author:

Hunter Catherine J.¹,Cai Xue²,Liebe Heather L.¹^ORCID,Golubkova Alena¹,Leiva Tyler¹

Affiliation:

1. Division of Pediatric Surgery, Oklahoma Children’s Hospital, Oklahoma City, OK 73104, Japan

2. Department of Surgery, The University of Oklahoma Health Sciences Center, 800 Research Parkway Suite 449, Oklahoma City, OK 73104, Japan

Abstract

Abstract: Necrotizing enterocolitis (NEC) is a devastating disease that primarily affects the gastro-intestinal tract of premature neonates. The diagnosis and treatment of NEC remain challenging. New biomarkers and potential treatments for NEC have emerged in recent years, leading to the potential of earlier therapeutic intervention and improved outcomes. This paper aims to provide a review of the most recent diagnostic indicators and therapeutics of NEC along with a brief overview of future directions of research into this disease.

Funder

Oklahoma Shared Clinical and Translational Resources

Publisher

Bentham Science Publishers Ltd.

Subject

Pediatrics, Perinatology and Child Health

Reference94 articles.

1. Meister A.L.; Doheny K.K.; Travagli R.A.; Necrotizing enterocolitis: It’s not all in the gut. Exp Biol Med (Maywood) 2020,245(2),85-95

2. Rich B.S.; Dolgin S.E.; Necrotizing enterocolitis. Pediatr Rev 2017,38(12),552-559

3. Neu J.; Walker W.A.; Necrotizing enterocolitis. N Engl J Med 2011,364(3),255-264

4. Gephart S.M.; Gordon P.V.; Penn A.H.; Changing the paradigm of defining, detecting, and diagnosing NEC: Perspectives on Bell’s stages and biomarkers for NEC. Semin Pediatr Surg 2018,27(1),3-10

5. Goldstein G.P.; Sylvester K.G.; Biomarker discovery and utility in necrotizing enterocolitis. Clin Perinatol 2019,46(1),1-17