Clinical Research on the Aortic Elasticity in Patients with Type 1 Diabetes Mellitus Complicated with Hypertension

Abstract

Background: To investigate the characteristics of aortic elasticity in type 1 diabetes mellitus (DM1) patients with hypertension using dual-source computed tomography (DSCT). Methods: Subjects were divided into four groups: 31 with hypertension (EH group), 28 with DM1 (DM1 group), 30 with hypertension and DM1 (DM1 + EH group), and 30 healthy volunteers (control group, CG). ECG-gated DSCT was used to measure the cross-sectional area of the aorta in diastole and systole and calculate the aortic elasticity (D). Analysis of variance and multiple linear regression were used for statistical analysis. Results: Compared with the CG, aortic elasticity (D) in the DM1 group patients was not significantly decreased. Compared with the EH group, the DM1 + EH group showed no significant change. The aortic elasticity (D) in the EH and DM1 + EH groups was significantly lower than that in the CG and DM1 group. Conclusion: DM1 slightly affects the aortic elasticity of the descending aorta, whereas hypertension exerts the main effect.