The Established Nuclear Medicine Modalities for Imaging of Bone Metastases

Author:

Jabeen Nazish1,Rasheed Rashid2,Rafique Asma1,Murtaza Ghulam1

Affiliation:

1. Department of Pharmacy, COMSATS Institute of Information Technology Abbottabad, Abbottabad, Pakistan

2. Institute of Nuclear Medicines, Oncology and Radiations (INOR), Ayub Medical Hospital, Abbottabad, Pakistan

Abstract

Background: The skeleton is one of the frequent site of metastases in advanced cancer. Prostate, breast and renal cancers mostly metastasize to bone. Discussion: Malignant tumors lead to significant morbidity and mortality. Identification of bone lesions is a crucial step in diagnosis of disease at early stage, monitoring of disease progression and evaluation of therapy. Diagnosis of cancer metastases is based on uptake of bone-targeted radioactive tracer at different bone remodeling sites. Conclusion: This manuscript summarizes already established and evolving nuclear medicine modalities (e.g. bone scan, SPECT, SPECT/CT, PET, PET/CT) for imaging of bone metastases.

Publisher

Bentham Science Publishers Ltd.

Subject

Radiology Nuclear Medicine and imaging

Cited by 3 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. All that illuminates on radionuclide imaging is not a metastatic lesion: Role of complementary imaging;Indian Journal of Musculoskeletal Radiology;2023-03-31

2. Targeting bone microenvironments for treatment and early detection of cancer bone metastatic niches;Journal of Controlled Release;2022-01

3. Evaluation of the Small-animal Nano Scan PET/CT System using 89Zr;Current Medical Imaging Formerly Current Medical Imaging Reviews);2021-03-16

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