Affiliation:
1. Department of Pharmacy, Institute of Pharmaceutical Research, GLA University Mathura, U.P, 281406, India
2. Department of Computer Engineering & Applications, GLA University Mathura, U.P, 281406, India
3. Parexel International,
DLF Building Tower F, 3rd Floor, Chandigarh Technology Park, Chandigarh-160101, India
Abstract
Abstract:
Inflammation is a part of the biological response of body tissues against harmful stimuli,
such as damaged cells, pathogens, irradiations, and toxic compounds. Numerous treatments, including
anti-inflammatory drugs that treat the condition of inflammation, are available for its management.
Because of the severe adverse effects associated with synthetic medications, phytotherapy
may be a promising and effective approach to treating inflammation. The therapeutic potential of
herbs is due to their capacity to target a variety of inflammatory mediators, including chemokines,
cytokines, nitric oxide, lipoxygenase, nuclear factor kappa-B, and arachidonic acid. Furthermore,
nanomedicine may be a valuable and effective formulation approach for overcoming the drawbacks
of phytoconstituents, such as their low bioavailability, high first-pass metabolism, and poor stability.
The current manuscript provides a thorough description of many phytoconstituents and herbal
plants that have great potential for treating inflammation-related diseases, as well as information on
their limitations, drug formulations, and regulatory issues.
Publisher
Bentham Science Publishers Ltd.
Subject
General Pharmacology, Toxicology and Pharmaceutics