Nanoneuroscience: Cutting-edge Approach for Disease Management

Author:

Malhotra Sakshi1,Jain Neha1ORCID,Rathee Jatin1,Kaul Shreya1,Nagaich Upendra1ORCID,Pandey Manisha23,Gorain Bapi4,Gupta Gaurav567

Affiliation:

1. Department of Pharmaceutics, Amity Institute of Pharmacy, Amity University, Noida, India

2. Department of Pharmaceutical Technology, School of Pharmacy, International Medical University, 57000, Kuala Lumpur, Malaysia

3. Department of Pharmaceutical Sciences, Central University of Haryana, Mahendergarh-123031, India

4. Department of Pharmaceutical Sciences and Technology, Birla Institute of Technology, Mesra, Ranchi 835215, Indi

5. School of Pharmacy, Suresh Gyan Vihar University, Jagatpura, Jaipur, 302017, India

6. Department of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai 602105, India

7. Uttaranchal Institute of Pharmaceutical Sciences, Uttaranchal University, Dehradun 248007, India

Abstract

Abstract: Neurological disorders (ND) have affected a major part of our society and have been a challenge for medical and biosciences for decades. However, many of these disorders haven't responded well to currently established treatment approaches. The fact that many active pharmaceutical ingredients can't get to their specified action site inside the body is one of the main reasons for this failure. Extracellular and intracellular central nervous system (CNS) barriers prevent the transfer of drugs from the blood circulation to the intended location of the action. Utilizing nanosized drug delivery technologies is one possible way to overcome these obstacles. These nano-drug carriers outperform conventional dosage forms in many areas, including good drug encapsulation capacity, targeted drug delivery, less toxicity, and enhanced therapeutic impact. As a result, nano-neuroscience is growing to be an intriguing area of research and a bright alternative approach for delivering medicines to their intended action site for treating different neurological and psychiatric problems. In this review, we have included a short overview of the pathophysiology of neurological diseases, a detailed discussion about the significance of nanocarriers in NDs, and a focus on its recent advances. Finally, we highlighted the patented technologies and market trends, including the predictive analysis for the years 2021-2028.

Publisher

Bentham Science Publishers Ltd.

Subject

General Engineering,Condensed Matter Physics,General Materials Science

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