Application of Fused Deposition Modelling (FDM) Method of 3D Printing in Drug Delivery

Author:

Long Jingjunjiao1,Gholizadeh Hamideh1,Lu Jun2,Bunt Craig3,Seyfoddin Ali4

Affiliation:

1. School of Science, Faculty of Health and Environmental Sciences,

2. School of Interprofessional Health Studies, Faculty of Health and Environmental Sciences,

3. Department of Agricultural Sciences, Faculty of Agriculture and Life Sciences, Lincoln University, Canterbury,, New Zealand

4. School of Science, Faculty of Health and Environmental Sciences, Auckland University of Technology, Private Bag 92006, Box A-25, Auckland 1142,, New Zealand

Abstract

Three-dimensional (3D) printing is an emerging manufacturing technology for biomedical and pharmaceutical applications. Fused deposition modelling (FDM) is a low cost extrusion-based 3D printing technique that can deposit materials layer-by-layer to create solid geometries. This review article aims to provide an overview of FDM based 3D printing application in developing new drug delivery systems. The principle methodology, suitable polymers and important parameters in FDM technology and its applications in fabrication of personalised tablets and drug delivery devices are discussed in this review. FDM based 3D printing is a novel and versatile manufacturing technique for creating customised drug delivery devices that contain accurate dose of medicine( s) and provide controlled drug released profiles.

Publisher

Bentham Science Publishers Ltd.

Subject

Drug Discovery,Pharmacology

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