Transfer Learning of the ResNet-18 and DenseNet-121 Model Used to Diagnose Intracranial Hemorrhage in CT Scanning

Author:

Zhou Qi1,Zhu Wenjie2,Li Fuchen3,Yuan Mingqing1,Zheng Linfeng4,Liu Xu1

Affiliation:

1. Medical College of Guangxi University, Nanning, Guangxi,China

2. Department of Emergency, The First Affiliated Hospital of Shantou University Medical College, Shantou 515041,China

3. College of Art and Science, Vanderbilt University, Nashville, Tennessee 37212, USA

4. Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, 200042,China

Abstract

Objective: To verify the ability of the deep learning model in identifying five subtypes and normal images in noncontrast enhancement CT of intracranial hemorrhage. Method: A total of 351 patients (39 patients in the normal group, 312 patients in the intracranial hemorrhage group) performed with intracranial hemorrhage noncontrast enhanced CT were selected, with 2768 images in total (514 images for the normal group, 398 images for the epidural hemorrhage group, 501 images for the subdural hemorrhage group, 497 images for the intraventricular hemorrhage group, 415 images for the cerebral parenchymal hemorrhage group, and 443 images for the subarachnoid hemorrhage group). Based on the diagnostic reports of two radiologists with more than 10 years of experience, the ResNet-18 and DenseNet-121 deep learning models were selected. Transfer learning was used. 80% of the data was used for training models, 10% was used for validating model performance against overfitting, and the last 10% was used for the final evaluation of the model. Assessment indicators included accuracy, sensitivity, specificity, and AUC values. Results: The overall accuracy of ResNet-18 and DenseNet-121 models were 89.64% and 82.5%, respectively. The sensitivity and specificity of identifying five subtypes and normal images were above 0.80. The sensitivity of DenseNet-121 model to recognize intraventricular hemorrhage and cerebral parenchymal hemorrhage was lower than 0.80, 0.73, and 0.76 respectively. The AUC values of the two deep learning models were above 0.9. Conclusion: The deep learning model can accurately identify the five subtypes of intracranial hemorrhage and normal images, and it can be used as a new tool for clinical diagnosis in the future.

Funder

National Natural Science Foundation of China

Foundation of Key Laboratory of Trusted Software

Guangxi Science and Technology Research Projects

Basic Ability Improvement Project

Guangxi Key Laboratory of Traditional Chinese Medicine Quality Standards

Publisher

Bentham Science Publishers Ltd.

Subject

Drug Discovery,Pharmacology

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