Acetylresveratrol (AC-Res): An Evolving Frontier in Modulating Gene Expression

Author:

Panigrahy Uttam Prasad1,Buchade Rahul Subhash2,S Sandhya3,N Anoop Kumar4,Gunjal Sachinkumar Dnyaneshwar5,Selvakumari E.6,Pandey Narendra Kumar7,Wal Ankita8

Affiliation:

1. Assam Downtown University, Sankar Madhab Path, Gandhi Nagar, Panikhaiti, Guwahati, Assam, India

2. SCES's Indira College of Pharmacy 'Niramay', S.No.89/2A, New Pune Mumbai Highway, Tathwade., Pune, Maharashtra, India

3. School of Health Sciences and Technology, University of Petroleum and Energy Studies, Bidholi Dehradun, Uttarakhand, India

4. School of Family Health Studies, Kerala University of Health Sciences, Kozhikode, Kerala, India

5. Amrutvahini College of Pharmacy, Sangamner, India

6. Mother Theresa Post Graduate and Research Institute of Health Sciences, Puducherry, India

7. School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab-144411, India

8. PSIT - Pranveer Singh Institute of Technology (Pharmacy) NH19 Kanpur Agra Highway, Kanpur, Uttar Pradesh, India

Abstract

Background: Acetylresveratrol (AC-Res), to date, is a powerful stilbene phytoalexin generated organically or as a component of a plant's defensive system, is a significant plant phenolic chemical portion and is investigated as a therapy option for a number of disorders. Owing to its inadequate stabilisation and considerable conformation rigidity, the utility of AC-Res as a medication is limited. Objective: The current review article outlined the structure of AC-Res, their methods of activity, and the latest technological progress in the administration of these molecules. It is conceivable to deduce that AC-Res has a variety of consequences for the cellular functions of infected cells. Methods: The literature survey for the present article was gathered from the authentic data published by various peer-reviewed publishers employing Google Scholar and PubMedprioritizing Scopus and Web of Science indexed journals as the search platform focusing on AC-Res pharmacological actions, particularly in the English language. Result: Despite its extensive spectrum of biological and therapeutic applications, AC-Res has become a source of increasing concern. Depending on the researchers, AC-Res possesses radioprotective, cardioprotective, neurological, anti-inflammatory, and anti-microbial potential. It also has anti-cancer and antioxidant properties. Conclusion: To avoid non-specific cytotoxicity, optimization efforts are presently emphasizing the possible usage of AC-Res based on nanocrystals, nanoparticles and dendrimers, and nanocrystals. Finally, while using AC-Res in biology is still a way off, researchers agree that if they continue to explore it, AC-Res and similar parts will be recognized as actual possibilities for a variety of things in the next years.

Publisher

Bentham Science Publishers Ltd.

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