Molecular Insights into RNA Modifications and their Role in Shaping Immune Responses and Tumor Microenvironments-Reference-Cited by-同舟云学术

Molecular Insights into RNA Modifications and their Role in Shaping Immune Responses and Tumor Microenvironments

Published:2025-01-21 Issue: Volume:25 Page:
ISSN:1566-5232
Container-title:Current Gene Therapy
language:en
Short-container-title:CGT

Author:

Ali Ashiq¹,Ajmal Tehreem²,Khatoon Aisha³,Akbar Kaynaat⁴,Irshad Urooj⁵,Murtaza Bilal⁶,ji Ziyi¹,Ali Abdullah⁷,Tanveer Qaisar⁸,Su Zhongjing¹

Affiliation:

1. Department of Histology and Embryology, Shantou University Medical College, China

2. Institute of Microbiology, University of Agriculture Faisalabad, Pakistan

3. Department of Pathology, University of Agriculture Faisalabad, Pakistan

4. Department of Zoology, Wildlife and Fisheries, Faculty of Sciences, University of Agriculture, Faisalabad 38040, Punjab, Pakistan

5. Department of Zoology, Superior University, Lahore, Pakistan

6. School of Bioengineering, Dalian University of Science and Technology, Dalian, China

7. Department of Theriogenology, University of Agriculture, Faisalabad, Pakistan

8. The Roslin Institute, Royal School of Veterinary Sciences, Edinburg, UK

Abstract

Abstract: RNA modifications play crucial roles in immune system development and function, with dynamic changes essential for diverse cellular processes. Innovative profiling technologies are invaluable for understanding the significance of these modifications in immune cells, both in healthy and diseased states. This review explores the utility of such technologies in uncovering the functions of RNA modifications and their impact on immune responses. Additionally, it delves into the mechanisms through which aberrant RNA modifications influence the tumor microenvironments immune milieu. Despite significant progress, several outstanding research questions remain, highlighting the need for further investigation into the molecular mechanisms underlying RNA modification's effects on immune function in various contexts.

Publisher

Bentham Science Publishers Ltd.