Nanomedicine: Innovative Strategies and Recent Advances in Targeted Cancer Therapy

Author:

Gautam Rupesh. K.12,Mittal Pooja3,Goyal Rajat4,Dua Kamal5,Mishra Dinesh Kumar2,Sharma Sanjay6,Singla Rajeev K.17

Affiliation:

1. Joint Laboratory of Artificial Intelligence for Critical Care Medicine, Department of Critical Care Medicine and Institutes for Systems Genetics, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China

2. Indore Institute of Pharmacy, IIST Campus, Rau, Indore-453331, Madhya Pradesh, India

3. Chitkara College of Pharmacy, Chitkara University, Rajpura-Punjab, India-140401

4. MM College of Pharmacy, Maharishi Markandeshwar (Deemed to be) University, Mullana-Ambala, Haryana, India

5. Discipline of Pharmacy Graduate School of Health Faculty of Health, Australian Research Centre in Complementary and Integrative Medicine (ARCCIM) University of Technology Sydney, Sydney, Australia

6. Shobhaben Pratapbhai Patel School of Pharmacy and Technology Management, SVKM'S NMIMS, Vile Parle (W), Mumbai-400 056, India

7. School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab-144411, India

Abstract

Abstract: Nanomedicine's application of nanotechnology in medicine holds tremendous potential for diagnosing and treating life-threatening diseases such as cancer. Unlike conventional therapies, nanomedicine offers a promising strategy to enhance clinical outcomes while minimizing severe side effects. The principle of drug targeting enables specific delivery of therapeutic agents to their intended sites, making it a more precise and effective therapy. Combination strategies, such as the co-delivery of chemotherapeutic drugs with nucleic acids or receptor-specific molecules, are being employed to enhance therapeutic outcomes. Nanocarriers and drug delivery systems designed using these approaches offer resourceful co-delivery of therapeutic agents for anticancer therapy. Targeted drug delivery via nanotechnology-based techniques has become an urgent need and has shown significant improvements in therapeutic implications, pharmacokinetics, specificity, reduced toxicity, and biocompatibility. This review discusses the extrapolation of nanomaterials for developing innovative and novel drug delivery systems for effective anticancer therapy. Additionally, we explore the role of nanotechnology-based concepts in drug delivery research.

Publisher

Bentham Science Publishers Ltd.

Subject

Pharmacology,Molecular Medicine,Drug Discovery,Biochemistry,Organic Chemistry

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