Instead of Calories, Should We Be Counting our Consumption of Exosomes and MicroRNAs?

Author:

Hirschi Kendal Dee1,Nalliah Vignesh1,Rhein Hormat Shadgou1

Affiliation:

1. Department of Pediatrics, Children’s Nutrition Center, Baylor College of Medicine, Houston, TX 77030, United States

Abstract

Abstract: The specific foods to eat for optimal nutrition remain ill-defined. Studies using plant-based diets or milk suggest that vesicles, termed exosomes, and small RNAs termed microRNAs (miRNAs) are health promoting components in foods. However, numerous studies refute the poten-tial of dietary cross-kingdom communication of exosomes and miRNAs. While research reinforces that plant-based diets and milk are healthy components of a well-rounded diet, the bioavailability and bioactivity of the exosomes and miRNAs present in plant-based diets and milk remain unclear. Further investigations of plant-based diet and milk exosome like particles may open a new era in application of food for overall health enhancement. In addition, the potential biotechnological plant-based diet and milk exosome like particles can aid in cancer treatment.

Funder

National Science Foundation

USDA, United States Department of Agriculture

National Institute of Health

Publisher

Bentham Science Publishers Ltd.

Subject

Orthopedics and Sports Medicine,Emergency Medicine,General Medicine

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