Affiliation:
1. Noida Institute of Engineering and Technology (Pharmacy Institute), 19, Knowledge Park-II, Greater Noida, 201306, U.P., India
2. Noida Institute of Engineering and Technology, 19 Knowledge Park-II, Greater Noida, 201306, U.P., India
3. School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, 144001, Punjab, India
Abstract
Abstract:
Bovine colostrum, also known as cow colostrum, is the first milk produced by cows after
giving birth. It is packed with natural macro-micronutrients, immunoglobulins, peptides, and proteins
and has been utilized in traditional medicine for centuries to treat a range of illnesses and problems.
Its therapeutic advantages are particularly significant in the treatment of respiratory problems,
growth factor augmentation, and other conditions. Numerous preclinical and clinical research studies
have demonstrated its therapeutic effects, including its ability to promote well-being, treat medical
conditions, and support animal husbandry. Bovine colostrum may assist therapy against COVID-19
due to its potential antiviral properties, which can slow the course of the disease. Bovine colostrum
contains bioactive components such as lactoferrin, which has antibacterial, anti-inflammatory, and
antiviral properties. Additionally, bovine colostrum may boost both the adaptive and innate immune
systems of humans. Colostrum's chemical composition differs from milk, with higher concentrations
of nutrients and physiologically active compounds such as enzymes, growth factors, immunoglobulins,
and hormones. The colostrum is crucial for the development of a newborn calf's immune system,
and the initial section of the colostrum has the highest concentration of insulin-like growth factors
(IGFs), which rapidly decline after that. While cow colostrum is generally considered safe when
consumed orally, it should be noted that rectal administration can function as an enema, and consuming
colostrum from infected cows can result in severe disorders such as bovine spongiform encephalitis
(BSE), also known as "mad cow disease" or other disorders. Therefore, it is crucial to use proper
sanitation and dosage of cow/ bovine colostrum for food or medicinal usage to avoid potential adverse
effects. This review article highlights the medical applications, constituents, and benefits of
cow colostrum, showcasing its potential as a natural remedy for health and wellness. However, it is
essential to exercise caution and obtain bovine colostrum from safe sources for optimal therapeutic
benefits.
Publisher
Bentham Science Publishers Ltd.