Vitamin D and Non-coding RNAs: New Insights into the Regulation of Breast Cancer-Reference-Cited by-同舟云学术

Vitamin D and Non-coding RNAs: New Insights into the Regulation of Breast Cancer

Published:2021-03 Issue:3 Volume:21 Page:194-210
ISSN:1566-5240
Container-title:Current Molecular Medicine
language:en
Short-container-title:CMM

Author:

Shahrzad Mohammad Karim¹,Gharehgozlou Reyhaneh²,Fadaei Sara³,Hajian Parastoo²,Mirzaei Hamid Reza²

Affiliation:

1. Department of Internal Medicine and endocrinology, Shohadae Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran,Iran

2. Cancer Research Center, Shohada Tajrish Hospital, Department of Radiation Oncology, Shahid Beheshti University of Medical Sciences, Tehran,Iran

3. Department of Internal Medicine and endocrinology, Beheshti University of Medical Sciences, Tehran,Iran

Abstract

Breast cancer, a life-threatening serious disease with a high incident rate among women, is responsible for thousands of cancer-associated death worldwide. Numerous investigations have evaluated the possible mechanisms related to this malignancy. Among them, non-coding RNAs (ncRNAs), i.e., microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs have recently attracted attention of researchers. In addition to recent studies for evaluating the role of ncRNAs in breast cancer etiology, some investigations have revealed that vitamin D has regulatory and therapeutic roles in breast cancer. Moreover, an important link between vitamin D and ncRNAs in cancer therapy has been highlighted. Herein, the aim of this study was to discuss the available data on the mentioned link in breast cancer.

Publisher

Bentham Science Publishers Ltd.

Subject

Molecular Biology,Molecular Medicine,General Medicine,Biochemistry

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