Recent Advances on Oximes Derivatives: Green Catalysis and Various Synthetic Routes

Abstract

Nitrogen-containing acyclic, cyclic, and heterocyclic compounds and their derivatives have received increasing attention as a source of therapeutic agents. Oximes are an interesting class of Nitrogen-containing compounds possessing a wide variety of applications. Over the last decade, the interest in oximes and their derivatives has intensified. Many oxime derivatives using several preparation methods have been developed and evaluated for their biological activities. Due to their importance, oximes are subjected to many chemical transformations with the use of different chemicals to obtain numerous new derivatives. As a part of the continuing interest in oxime derivatives, we aim in this review to explore the green chemistry principles for the synthesis of oxime derivatives, as it offers promising pathways to more sustainable synthesis techniques that minimize waste and energy consumption and avoid hazardous methods. Additionally, it could inspire and stimulate researchers from various disciplines, such as chemists, biologists, and materials scientists to explore new applications for oximes derivatives.