Affiliation:
1. Hubei Key Laboratory of Tumor Microenvironment and Immunotherapy, China, Three Gorges University, Yichang, China
2. Medical College of China Three Gorges University, Yichang, China
Abstract
Abstract:
The incidence of malignant tumors is rising rapidly and tends to be in the
younger, which has been one of the most important factors endangering the safety of human
life. Ultrasound micro/nanobubbles, as a noninvasive and highly specific antitumor
strategy, can reach and destroy tumor tissue through their effects of cavitation and acoustic
perforation under the guidance of ultrasound. Meanwhile, micro/nanobubbles are now
used as a novel drug carrier, releasing drugs at a target region, especially on the
prospects of biomaterial-modified micro/nanobubbles as a dual modality for drug delivery
and therapeutic monitoring. Successful evaluation of the sonoporation mechanism(s),
ultrasound parameters, drug type, and dose will need to be addressed before translating
this technology for clinical use. Therefore, this paper collects the literature on the experimental
and clinical studies of ultrasound biomaterial-modified micro/nanobubbles therapy
in vitro and in vivo in recent years.
Publisher
Bentham Science Publishers Ltd.
Subject
Pharmacology,Molecular Medicine,Drug Discovery,Biochemistry,Organic Chemistry
Cited by
3 articles.
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