Application of Aptamer-based Hybrid Molecules in Early Diagnosis and Treatment of Diabetes Mellitus: From the Concepts Towards the Future

Author:

Ahmadi Sepideh1,Rabiee Navid2,Rabiee Mohammad3

Affiliation:

1. Department of Biology, Faculty of Basic Sciences, University of Zabol, Zabol, Iran

2. Department of Chemistry, Shahid Beheshti University, Tehran, Iran

3. Biomaterials Group, Faculty of Biomedical Engineering, Amirkabir University of Technology, Tehran, Iran

Abstract

Aptamers have several positive advantages that made them eminent as a potential factor in diagnosing and treating diseases such as their application in prevention and treatment of diabetes. In this opinion-based mini-review article, we aimed to investigate the DNA and RNA-based hybrid molecules specifically aptamers and had a logical conclusion as a promising future perspective in early diagnosis and treatment of diabetes.

Publisher

Bentham Science Publishers Ltd.

Subject

Endocrinology,Endocrinology, Diabetes and Metabolism

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3. Chatterjee B, Pancholi J, Kevalia J, Kothari V, Pandya P, Bhatt U. Significance of molecular markers and dna based technology in research and standardization of medicinal plants: A review.

4. Jayasena SD. Aptamers: An emerging class of molecules that rival antibodies in diagnostics.

5. Roth A, Breaker RR. The structural and functional diversity of metabolite-binding riboswitches.

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