Impact of UPLC-MS in Food and Drug/Metabolite Analysis

Author:

Semwal Ankit1ORCID,Dogra Raghav1ORCID,Verma Kritika1ORCID,Bhatia Rohit1ORCID

Affiliation:

1. Department of Pharmaceutical Analysis, Indo-Soviet Friendship College of Pharmacy (ISFCP), Moga 142001, India

Abstract

The hyphenation of Ultra-Performance Liquid performance (UPLC) with mass spectrometry (MS) has emerged as a powerful tool in analytical research due to its advanced sensitivity, resolution and speed. Its advanced instrumentation, specialized columns, separation at ultra-high pressure and sophisticated software are the distinguishing features as compared to the traditional separating techniques. It has a wide range of applications in various fields such as analysis of food stuffs, drug metabolites, beverages, toxicology, soil samples and micronutrient analysis. In the present compilation, authors have highlighted the applicability of UPLC-MS in the analysis of food stuffs and drug metabolites along with the various optimized analytical conditions and obtained results.

Publisher

Bentham Science Publishers Ltd.

Subject

Pharmaceutical Science,Molecular Medicine,Biochemistry,Biophysics

Reference82 articles.

1. Naushad M.; Khan M.R.; Alothman Z.A.; Ultra Performance Liquid Chromatography Mass Spectrometry Evaluation and Applications in Food Analysis, 1 2015,1-15

2. Fenn J.B.; Mann M.; Meng C.K.; Wong S.F.; Whitehouse C.M.; Electrospray ionization for mass spectrometry of large biomolecules. Science 1989,246(4926),64-71

3. Chawla G.; Ranjan C.; Principle, instrumentation, and applications of UPLC: A novel technique of liquid chromatography. Open Chem J 2016,3(1),1-16

4. LCGC Solution for Seperation Scientist Available from:, ext-link-type="uri" xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="http://www.chromatographyonline.com">http://www.chromatographyonline.com

5. Nguyen D.T.; Guillarme D.; Rudaz S.; Veuthey J.L.; Fast analysis in liquid chromatography using small particle size and high pressure. J Sep Sci 2006,29(12),1836-1848

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