The Application of Hydrogels in the Treatment of Intrauterine Adhesions-Reference-Cited by-同舟云学术

The Application of Hydrogels in the Treatment of Intrauterine Adhesions

Published:2025-02 Issue:13 Volume:31 Page:1057-1066
ISSN:1381-6128
Container-title:Current Pharmaceutical Design
language:en
Short-container-title:CPD

Author:

Rajabloo Yasamin¹^ORCID,Al-Asady Abdulridha Mohammed²³⁴,Akbarzadeh Hanieh¹,Avan Amir⁵⁶,Khazaei Majid⁵⁷,Ryzhikov Mikhail⁸,Hassanian Seyed Mahdi⁵⁹

Affiliation:

1. Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

2. Department of Medical Sciences, Faculty of Nursing, University of Warith Al-Anbiyaa, Karbala, Iraq

3. Department of Medical Sciences, Faculty of Dentistry, University of Kerbala, Karbala, Iraq

4. Department of Pharmacology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

5. Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

6. Faculty of Health, School of Biomedical Sciences, Queensland University of Technology (QUT), Brisbane, QLD 4059, Australia

7. Department of Medical Physiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

8. School of Medicine, Saint Louis University, St. Louis, MO 63103, USA

9. Department of Clinical Biochemistry, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Abstract

Intrauterine Adhesions (IUA) are a significant cause of infertility and miscarriage, often resulting from trauma to the endometrium. While hysteroscopic adhesiolysis is the primary treatment, the use of hydrogels as anti-adhesion barriers and drug delivery systems is gaining traction for improving patient outcomes. This review aims to explore various hydrogel types, their role in tissue repair, and the integration of stem cell therapy. Recent advancements in biomaterial scaffolds have demonstrated potential in preventing adhesion recurrence and promoting endometrial regeneration. These emerging treatments provide promising avenues for enhancing the efficacy of traditional therapies in IUA management.

Funder

Mashhad University of Medical Sciences

Publisher

Bentham Science Publishers Ltd.

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