Affiliation:
1. Department of Science Education, School of Education, Zhejiang International Studies University, Hangzhou, China
Abstract
Abstract:
4-Hydroxyquinoline-2(1H)-ones exhibit multiple biological activities, and studying their
synthetic methods is of great significance. In the presence of tetramethylguanidine and silver nitrate,
4-hydroxyquinoline-2(1H)-ones were efficiently synthesized from 2-ethynylanilines and carbon dioxide
under atmospheric pressure. The reaction conditions, such as types of silver catalysts and reaction
solvents, were optimized, and the applicability of the substrate was preliminarily investigated. This
method provides an alternative pathway for the synthesis of 4-hydroxyquinoline-2(1H)-ones and the
conversion and utilization of carbon dioxide.
Publisher
Bentham Science Publishers Ltd.