The Synthesis of 2-substituted Benzo[b]furans Catalyzed by Ni/5-Bromo- 2,2’-bipyridine-Reference-Cited by-同舟云学术

The Synthesis of 2-substituted Benzo[b]furans Catalyzed by Ni/5-Bromo- 2,2’-bipyridine

Published:2022-12 Issue:12 Volume:19 Page:1149-1153
ISSN:1570-1786
Container-title:Letters in Organic Chemistry
language:en
Short-container-title:LOC

Author:

Rong Zhou¹,Huan-huan Wang¹,Yu-qin Li¹,Yan-li Ding¹,Xiao-li Qin¹,Jing Sha²,Ping Li¹,Lu Jin¹

Affiliation:

1. College of Chemistry and Chemical Engineering, Xinjiang Agricultural University, Urumqi, China

2. International Academy, Guizhou University of Finance and Economics, Guiyang, China

Abstract

Abstract: A tandem system that enabled the synthesis of 2-substituted benzo[b]furans from 2- halophenols and aryl acetylenes catalyzed by Ni/5-bromo-2,2’-dipyridine was explored. The protocol was found effective for one-pot cascade coupling cyclization reaction producing benzo[b]furan compounds, and heteroaryl substrates were observed to be compatible for this system as well, giving corresponding products in 20-70% yields.

Funder

Natural Science Foundation of China

Natural Science Foundation of Xinjiang Province

Publisher

Bentham Science Publishers Ltd.

Subject

Organic Chemistry,Biochemistry

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