Affiliation:
1. Regenerative Medicine, Organ Procurement and transplantation Multi Disciplinary Center, Razi Hospital, School of
Medicine, Guilan University of Medical Sciences, Rasht, Iran
Abstract
Abstract:
Recent advances in electrospinning have transformed the process of fabricating ultrafine
nano-fiber scaffolds with side benefits to drug delivery systems and delivery systems in general.
The extremely thin quality of electrospun nanofiber scaffolds, along with an effective area of high
specificity and a stereological porous structure, capacitates them for the delivery of biomolecules,
genes, and drugs. Accordingly, the present study gives a close preface on certain approaches to
incorporating drugs and biomolecules into an electrospun nanofiber scaffold, including blending,
surface engineering and modification, coaxial electrospinning and emulsion-based systems. The
study further elaborates on certain biomedical applications of nanofibers as drug delivery systems,
with case examples of Transdermal systems/ antibacterial agents/ wound dressing, cancer treatment,
scaffolds for Growth Factor delivery and carriers for stem cell delivery systems.
Publisher
Bentham Science Publishers Ltd.
Subject
Biomedical Engineering,Pharmaceutical Science
Cited by
4 articles.
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