Affiliation:
1. Department of Pharmaceutics, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Ooty, India
Abstract
:
At present, treatment methods for cancer are limited, partially due to the solubility, poor
cellular distribution of drug molecules and the incapability of drugs to cross the cellular barriers.
Carbon Nanotubes (CNTs) generally have excellent physio-chemical properties, which include
High-level penetration into the cell membrane, high surface area, and high capacity of drug-loading
by circulating modification with biomolecules, projecting them as an appropriate candidate to
diagnose and deliver drugs to Prostate Cancer (PCa). Additionally, the chemically modified CNTs
possess excellent 'biosensing' properties, thus helping them detect the PCa easily without a fluorescent
agent and additionally, targeting the particular site of PCa. In this way, drug delivery can accomplish
high efficacy, enhanced permeability with less toxic effects. While CNTs have been mainly
engaged in cancer treatment, a few studies are focused on the diagnosis and treatment of PCa.
Here, we have meticulously reviewed the current progress of the CNTs-based diagnosis and the targeted
drug delivery system for managing and curing PCa.
Publisher
Bentham Science Publishers Ltd.
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