Erythrocyte-based Drug Delivery: How Far from Clinical Application?-Reference-Cited by-全球学者库

Erythrocyte-based Drug Delivery: How Far from Clinical Application?

Published:2024-01 Issue:1 Volume:21 Page:52-64
ISSN:1567-2018
Container-title:Current Drug Delivery
language:en
Short-container-title:CDD

Author:

Jiang Yuan¹,Yuan Yi²,Peng Feng¹,Deng Yi¹,Ren Chao¹,Liu Chongzhi¹,Dong Hai¹,Tu Tao¹

Affiliation:

1. Clinical Medical College, The First Affiliated Hospital of Chengdu Medical College, Chengdu, China

2. Department of Orthopedic, Dazhou Integrated TCM & Western Medicine Hospital, Dazhou Second People’s Hospital, Dazhou, China

Abstract

Abstract: Erythrocytes are responsible for delivering oxygen throughout the body. They have become suitable drug carriers due to outstanding advantages, such as a long lifespan in circulation, high biosafety, and low immunogenicity. Although erythrocyte-based drug delivery has good application prospects and has become a research hotspot in related fields, the application of erythrocyte-based drug delivery systems is rare in the clinic now. In this review, we discuss the characteristics of erythrocytes, diverse drug-loading approaches, and research progress of erythrocyte-based drug delivery systems. Finally, we explore the challenges of erythrocyte-based drug delivery in clinical application.

Funder

Science and Technology Department of Sichuan province

Sichuan Applied Psychology Research Center of Chengdu Medical College

Special Nursing Project of Special Scientific Research Fund of First Affiliated Hospital of Chengdu Medical College

Publisher

Bentham Science Publishers Ltd.

Subject

Pharmaceutical Science

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