Complementary Medication for COVID-19 Outbreak Concerns in the Leprosy Community - A Passionate Proposal

Author:

Thangaraju Pugazhenthan1ORCID,Venkatesan Sajitha2ORCID,Gurunthalingam Meenalotchini Prakash1,Velmurugan Hemasri1ORCID,Sudha TY Sree3ORCID,K Thangadurai4,Thangaraju Eswaran5,Balasundaram Mahesh Kumar1ORCID

Affiliation:

1. Department of Pharmacology, All India Institute of Medical Sciences, Raipur, Chhattisgarh, India

2. Department of Microbiology, All India Institute of Medical Sciences, Raipur, Chhattisgarh, India

3. Department of Pharmacology, All India Institute of Medical Sciences, Deogarh, Jharkhand, India

4. JSA Siddha Medical College, Ulundurpet, Tamil Nadu, India

5. AKT College of Engineering, Kallakurichi, Tamilnadu, India

Abstract

Abstract: The number of COVID-19-positive cases continues to climb, causing alarm around the world. The Nilavembu (Andrographis paniculata) Kudineer of Siddha medicine, an alternative medicine practiced in India, has already been shown to be beneficial in viral outbreaks like Chikungunya and Dengue fever. Several investigations have demonstrated that these herbs have anti-inflammatory, analgesic, antipyretic, antibacterial, and antiviral activities against the Herpes simplex virus and Ebstein Barr virus. This herbal remedy has also been shown to have a low risk of negative side effects. There is currently no approved pharmaceutical treatment for COVID-19. Using the phrases 'COVID-19,' 'Ayush,' 'Siddha,' and 'Leprosy,' we searched other databases such as Google, Embase, ScienceDirect, and the Clinical Trial Registry of India. In another research on Siddha treatment, Kabasura Kudineer, a decoction of 15 herbal items was discovered to have activity against the spike protein of SARS COV-2 using an in-silico compound method. As there are no effective treatments available for the prevention and treatment of mild to moderate cases, these two medicines, Nilavembu Kudineer, and Kabasura Kudineer can be used as part of a COVID-19 prophylaxis using a combination of modern and alternative medicine.

Publisher

Bentham Science Publishers Ltd.

Subject

Complementary and alternative medicine,Drug Discovery

Reference38 articles.

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4. Thangaraju P.; Arulmani M.; Venkatesan S.; Gurunthalingam M.; Thangaraju E.; COVID-19 and leprosy-hurdles and possible solutions. Asian Pac J Trop Med 2020,13(10),472-473

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